Endocrine Abstracts

Background: Cardiovascular disease remains the leading cause of death worldwide, affecting both sexes. Awareness and prevention practices aiming to control cardiovascular risk in women remain inadequate. On the other hand, circulating amyloid β 1-40 (Aβ1-40) is a proatherogenic peptide, closely linked with the process of aging. We aimed to evaluate the possible association between the progression of atherosclerosis in postmenopausal women and the role of Aβ1-40 ...

Background: A large body of evidence is supporting that the incidence of adverse cardiovascular events is increasing signfiicantly after the menopausal transition. Primary prevention practices continue to propose evolving algorithms, in an attempt to accurately estimate the actual female cardiovascular risk at midlife. Irrespectively of these attempts, considerable unrecognized cardiovascular disease (CVD) risk remains unexplained, beyond traditional risk factors (TRFs). On th...

Background: Recent data is indicating that levels of circulating amyloid β 1-40 (αβ1-40), a proatherogenic aging peptide, may be considered as a novel biomarker in cardiovascular disease (CVD). Postmenopausal women represent a population with substantial unrecognized CVD-risk, which would benefit from identification of novel cardiovascular risk markers.Aim: To explore the role of plasma Aβ1-40 and its patterns of change over time in a...